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Each year, an estimated 7·7 million deaths are associated with bacterial infections, 1·27 million of which are caused by bacterial pathogens resistant to the antibiotics available to treat them.
Rising antimicrobial resistance has been documented over the past two decades, and projections from high-income countries predict resistance to third line antibiotics—the last-resort drugs—could be 2·1 times higher in 2035 compared to 2005.
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The scope of the antimicrobial resistance challenge
Burden of bacterial antimicrobial resistance in low-income and middle-income countries
Urgent breast cancer challenges can—and should—be tackled. The Lancet Breast Cancer Commission report shows glaring inequities, with many groups with breast cancer being systematically left behind and forgotten. This is a global blunder.
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Despite a reduction in prevalence since 1990, anaemia remains a significant global health challenge. Substantial variation in anaemia burden exists by age, sex, and geography. Although anaemia burden dramatically decreases with socioeconomic development in general, the burden in sub-Saharan Africa and south Asia is significantly worse than expected. Cause-specific burden estimates vary substantially by location, and can be used to design locally relevant health interventions aimed at improving anaemia management and prevention.
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Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990–2021: findings from the Global Burden of Disease Study 2021
Progress in improving global cancer surgery outcomes has been slow to meet rising demand—a new Lancet Oncology Commission puts forward pragmatic, geographically contextualised solutions for transformative and equitable change.
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Global Cancer Surgery: pragmatic solutions to improve cancer surgery outcomes worldwide
Members of the WHO Task Force of AMR Survivors share their personal experiences with Antimicrobial Resistance.
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Antimicrobial resistance survivors: calling the world to action
The Lancet Series on Antimicrobial Resistance: The need for sustainable access to effective antibiotics (Series)
Despite tremendous advances in breast cancer research and treatment over the past three decades—leading to a more than 40% reduction in breast cancer mortality in some high-income countries—inequities remain, with many groups being systematically left behind, ignored, and even forgotten. This is a global blunder, argues a new Lancet Commission. In their report, authors set out recommendations to tackle the urgent challenges in breast cancer.
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The 2023 report of the Lancet Countdown on health and climate change reveals the growing health harms of climate change, and the imperative for a health-centred response in a world facing irreversible harms.
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